Thanks for posting your query.
Loose motions could be due to metformin (present in Zoryl M) or due to Neksium.
Do you have vomiting/ fever/ spasmodic abdominal pain
along with watery diarrhea?
With the available described details, there could also be possibility of acute gastroenteritis
You should consult with internal medicine specialist and should go for thorough check up.
You should also go for complete blood count
imaging, and serum electrolytes.
You should take complete antibiotic therapy, antispasmodics, probiotics, antipyretics, if needed.
You should maintain your hydration by taking potassium rich liquids.
Frequent loose diarrhea may cause loss of potassium with weakness and fatigue feeling.
Avoid milk and all milk related products.
You should take Rantac and combination of glimipride & pioglitazone
Dr. Mayank Bhargava