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(ALT) and Aspartate Transaminase (AST) are enzymes secreted in liver
. A value above 100 is considered significant. Accordingly what your father had was a significant rise in liver enzymes. Liver enzymes are elevated due to inflammatory liver condition (hepatitis), alcohol consumption, tumours and so on. In the absence of significant clinical history, drug intake and alcohol consumption, all physician perform investigations such as serological tests for hepatitis and ultrasound
scans to rule out other causes.
is diagnosed based on positive serological tests. Ultrasound examination can pick up structural causes such as tumour.
High blood sugars and high blood pressure
are not directly responsible for high liver enzymes and development of tumour. Discuss with his gastroenterologist for the next steps of management.
Hope this answers your query.
Wish your father a good recovery.