29 yo developmentally disabled adopted daughter, (Hx. precocious puberty age 6, MRI negative, depolupron age 7 - 12), overweight but no other medical problems . Had sudden onset of psychosis (paranoid, aggitated and short term memory loss) lasting 7 days - 4 days were pretty bad, 3 days with improvement each day. Started her mensural period two days after onset of psychotic episode. ED gave her antipsychiotics and Ativan.... only gave her meds for 3 days and she is on nothing now and back to normal mental state. No other paranoia or episodes of pychosis previously.

Took her for medical check up - labs pending. MRI of brain w/o and w/ contrast shows empty sella - otherwise negative.

Birth mother paranoid schizophrenic - so somewhat worried about that possibility - but would seem like late onset?

Now the Q: Can hormonal imbalances cause such a drastic event (very sudden onset of psychosis)? Given that it started a few days before her period and the MRI shows empty sella, does this possible match up for a hormonal imbalance to trigger psychosis?