welcome to Healthcare Magic.Venlafaxine
can associated with weight gain in some cases. If your depression
has improved on this medicine then in such condition it will be better to monitor your weight and implement lifestyle measures to reduce your weight.
If your hot flushes and muscle problem started after initiation of venlafaxine, then it may be side effect related to it. As you are already on venlafaxine for 2 years. If hot flushes and muscle problem are recent in onset then it is less likely due venlafaxine.
Apart from that there is need to rule out other causes for weight gain (Hypothyroidism
), hot flushes (menopause
in female) and muscle problem after evaluation and investigation.
Wish you all the best.
Dr Ashish Kumar Mittal