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Dr. Andrew Rynne
MD
Dr. Andrew Rynne

Family Physician

Exp 50 years

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Declining Platelet Count. Treatment?

Hi.

I have steadily declining platelet count. Ferritin is also low. Numbers are as follows

Date           Platelet           Ferritin
                    
                    
03/24/06          139          
                    
04/04/08          138          
                    
04/10/09          152          
                    
01/19/12           141          18
                    
04/05/13          120          13
                    
07/22/13          113          24
                    
08/20/13          108          

I had an ultrasound and Doctor said i had a slightly enlarged spleen. I am obviously concerend and am scheduled for another round of test sin November, What are yur thoughts?
Mon, 14 Oct 2013
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General & Family Physician 's  Response
Hello,
Thanks for the query to H.C.M. Forum.
As you mentioned in this query that there is progressive depletion of platelets count and also there is enlargement of spleen as spleen enlargement is very important in this case .
We call this condition as Thrombocytopenia , may be due to ,
1 Decreased bone marrow production , diagnosis can be confirmed by blood film from bone marrow aspiration.
2 Increased splenic sequestration as this is evident ( as spleen is already enlarged)
3 Accelerated destruction of platelets as in case of dengue fever and many other high grade fever. Diagnosis can be confirmed by C B C and file for M P.
In my opinion consult a hematologist and get his opinion as spleen is also involved .
Good luck. Dr. HET
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Declining Platelet Count. Treatment?

Hello, Thanks for the query to H.C.M. Forum. As you mentioned in this query that there is progressive depletion of platelets count and also there is enlargement of spleen as spleen enlargement is very important in this case . We call this condition as Thrombocytopenia , may be due to , 1 Decreased bone marrow production , diagnosis can be confirmed by blood film from bone marrow aspiration. 2 Increased splenic sequestration as this is evident ( as spleen is already enlarged) 3 Accelerated destruction of platelets as in case of dengue fever and many other high grade fever. Diagnosis can be confirmed by C B C and file for M P. In my opinion consult a hematologist and get his opinion as spleen is also involved . Good luck. Dr. HET