Thanks for your query.
You have not mentioned the doses of drugs, particularly ms contin and methotrexate
You can try anti-TNF therapy, which is very expensive, but effective in majority of cases. However, efficacy is less in long-standing rheumatoid arthritis
Alternatively, instead of indomethacin
, take Leflunamide; dose of Methotrexate can be increased (under strict supervision) to maximum permissible dose; dose of oral steroids can be increased for a short period and then tapered off; HCQS and Sulfasalazine
can be added if not used earlier.
I suggest that you consult a Rheumatologist
, who knows what is best for you.
Hope I have answered your query.
Dr. Rakesh Karanwal