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Dr. Andrew Rynne
MD
Dr. Andrew Rynne

Family Physician

Exp 50 years

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Crohns Disease, Raised Lipase Levels. Reason?

Hello and thank you for your time! My son is 31 years old and has been recently diagnosed with Crohns after 2 colonoscopies. He is physically active with exercise and sports.. Recently his lipase level came back extremely high, around 600. His Gastro Dr. followed with a colonoscopy and a CAT scan. Nothing unexpected was found and his liver, pancreas and gall bladder appeared normal. His next blood test showed lipase level still above 500. He is having an upper endoscopy in 2 days. He is worried and fears the worst ( pancreatic cancer ). Why would his lipase levels be so high in your opinion? Are there specific questions he should ask of his Dr.? Or specific tests you would suggest?
Fri, 19 Oct 2012
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Gastroenterologist 's  Response
HI
Does he have abdominal pain
lipase usually rises with pancreatic inflammation not with cancer
so don t think u shd worry
also lipase 3 times normal limit is imp 600 may not be relevant in that case
if CT is normal then no worry
also sme drugs used n treatment of crohns may cause pancreatitis
esp azatioprine
just check his drug history and also dont worry
Hope this answers your query. I will be glad to answer the follow up queries that you have.
Please accept my answer in case you do not have further queries.
Wishing him good health.
Regards.
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Crohns Disease, Raised Lipase Levels. Reason?

HI Does he have abdominal pain lipase usually rises with pancreatic inflammation not with cancer so don t think u shd worry also lipase 3 times normal limit is imp 600 may not be relevant in that case if CT is normal then no worry also sme drugs used n treatment of crohns may cause pancreatitis esp azatioprine just check his drug history and also dont worry Hope this answers your query. I will be glad to answer the follow up queries that you have. Please accept my answer in case you do not have further queries. Wishing him good health. Regards.