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Dr. Andrew Rynne
MD
Dr. Andrew Rynne

Family Physician

Exp 50 years

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Could The Overactive Thyroid Be The Cause For Failure Of Embryo Implantation?

I have just had my fourth failed IVF attempt. It took three attempts and no fertilisation before we were advised to do a fragmentation test on the sperm and my husband fragmentation is 61.1%. We got a donor and just had another cycle which unfortunately failed - had one grade 5 embyro and one grade 4 replaced on day 5, but they didn t implant. I am on carbimazole for a overactive thyroid which is stable the doctor tells me(taking 5mg every second day and 10mg the others) would this affect my chances of embyro implantation??
Thu, 26 May 2016
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Infertility Specialist,  's  Response
Hi... Failed fertilization in past 3 attempts and DNA fragmentation index 0f 61.6 % is definitely worrisome. Good you have decided for donor. As your thyroid level is stable with medications that should not be an issue to prevent implantation.
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Could The Overactive Thyroid Be The Cause For Failure Of Embryo Implantation?

Hi... Failed fertilization in past 3 attempts and DNA fragmentation index 0f 61.6 % is definitely worrisome. Good you have decided for donor. As your thyroid level is stable with medications that should not be an issue to prevent implantation.