Thank you for your quiery. You have had recurrent duodenal ulcers.
You have been treated appropriately with a PPI, Nexium
. You were
also tested and treated for H.Pylori which is also very appropriate.
There are a number of cases where H.Pylori can come back even
after successful therapy. I would like you to be re-tested for the
same. You can have a H.Pylori stool antigen test or a breath test
The one condition that causes recurrent ulcers or multiple ulcers
is called "Zollinger-Ellison Syndrome". This is associated with a
in the pancreas
that produces gastrin which causes excess
acid and ulcers.
The way to diagnose this is by doing Fasting Gastrin levels in the
blood at least on three separate occasions. Increased level of
"Chromogranin A is a marker for these type of tumors. There
are also Secretin stimulation test and acid measurement that
can help with the diagnosis. Get your blood calcium levels checked.
I hope you can discuss these with your doctor.
I wish you well.