Hi Amit, Thanks for writing in to Healthcare Magic! The first thing I would like to tell you is that the Persistent cold is not a disease in itself. Rather is a phenomenon, an maladjustment disorder with environment. Observe carefully you would find a cause that is bringing the problem again and again. Most common culprit is sudden change in temperature. Take an example- you are sleeping in the night, do not keep yourself covered and get cold, solution wear a bit thick donned top to bottom cover night suit. Similar situation arises when you move out from warm room to outside and you are not well clad so sudden change in temperature. You may not be taking enough water before going to bed- get thirsty early morning, drink large amount of water in one go, get cold due to sudden change in temperature. You may love going out in air immediately after bath to enjoy cooling and catch cold. These examples may look boring to you but they are culprits in more than half of the persons who suffer cold round the year.Viruses are well known cause of cold but not in such cases, this type of problem is called vasomotor rhinitis.One simple remedy is take a combination like Sinarest/Wikoryl tablet stat with the first symptom and take rest in bed for half an hour, the problem would not increase beyond.Try these options and you will forget the cold, I hope. Get a check up for any asthmatic tendency if that is thare then you would need bronchodilators as well. If you have any further query please let me know I would try to answer it for you. Wish you a great health!