Thanks for writing in.
As you say, your wife 43 years of age had continuous mild bleeding with USG findings pointing towards echogenic hypertrophied endometrium.
Generally speaking an endometrium thickness upto 10 mm is taken as normal. SInce your wife is approaching the menopausal age, there can be phases of irregular bleeding in many women. However, please do not hesitate to take gynaecological consultation immediately (even if the bleeding has stopped). Please go for a biopsy
if the consulting gynaecologist insists.
As for cancer, prevention is the best cure and so is early detection.
Without a biopsy its difficult to confirm in some patients.