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Dr. Andrew Rynne
MD
Dr. Andrew Rynne

Family Physician

Exp 50 years

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Chronic Urticaria Since Long, Blood Test Showed No Food Allergy. Any Suggestion?

Im 34 yrs old and been suffering with chronic urticaria for the past 9mos. ive been to 2 dermotologist and 2 allergist recently had a blodd test that showed no food allergies . Now I took it upon mysmyself to get tested for H-pylori test after doing some research i ve changed my diet. And I still have the break outs. Do you have any siggestions?
Thu, 19 Jul 2012
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Allergist and Immunologist 's  Response
Hello,
It seems that your urticaria is truly idiopathic in nature, but I presume that the H pylori test (during endoscopy) was negative as your results of food allergies.
Thyroid function with TPO antibodies should be checked as occasionally thyroid imbalance can be the cause.
You will need Allegra 180mg AM plus 90mg PM and cetirizine 10mg (midday) with 10mg reserve at night (PM) or hydroxyzine 25/50mg ONLY at night to control the urticaria. There are various combinations of antihistamines you can use that give you best control. Anti-IgE therapy (Omalizumab) or high-dose IVIG are expensive traetment options especially when hydroxycholoroquine or ciclosporin fails after antihistamines have not worked.
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Dermatologist Dr. Puvvula Kishore Kumar's  Response
Hi....dear eilee..,
Thanks for using HCM..,
It could be CHRONIC IDIOPATHIC URTICARIA..,
due to Ig E mediation..,
So go for Morning Fexofenadine Hcl...ALLEGRA 180 mg ..,
Night times use LEVOCETRIZINE...10 mg ..,
Tab Ranitidine 150 mg before breakfast..,
Apply calamine lotion on affected part..,
Tab Dicaris....Levamisole 150 mg weekly once for 3 weeks.,
thanQ
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Chronic Urticaria Since Long, Blood Test Showed No Food Allergy. Any Suggestion?

Hello, It seems that your urticaria is truly idiopathic in nature, but I presume that the H pylori test (during endoscopy) was negative as your results of food allergies. Thyroid function with TPO antibodies should be checked as occasionally thyroid imbalance can be the cause. You will need Allegra 180mg AM plus 90mg PM and cetirizine 10mg (midday) with 10mg reserve at night (PM) or hydroxyzine 25/50mg ONLY at night to control the urticaria. There are various combinations of antihistamines you can use that give you best control. Anti-IgE therapy (Omalizumab) or high-dose IVIG are expensive traetment options especially when hydroxycholoroquine or ciclosporin fails after antihistamines have not worked.