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Dr. Andrew Rynne
MD
Dr. Andrew Rynne

Family Physician

Exp 50 years

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Child Suffering From Mitochondrial Disease Affecting Brain, Have Dental Problems. Are They Related?

My 5-year-old daughter may suffer from a mitochondrial disease , affecting her brain (we re still in the process of getting a diagnosis). She also develops cavities very quickly. It seems like no matter what we do, her teeth rot right out of her mouth. She just had surgery to remove 2 of her 3 remaining baby molars and had 4 root canals and crowns. Could there be a connection between her dental problems and her possible mito disease?
Mon, 4 Feb 2013
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Dentist 's  Response
Hi,
Thank you for the query.
Mitochondrial disese is a result of failure from the mitochondria, specialized compartments present in every cell of the body except RBC. when they fail, less energy is generated in the cell leading to cell injury and death of cell follows.
They appear to cause most damage to cells of brain,skeletal muscles, kidney, endocrines and respiratory system leading to symptoms including loss of motor control , muscle weakness and pain,GI disorders , swallowing difficulty and poor growth, seizures,developmental delay and susceptability to infections.
Yes, there is chance for the dental problems (cavities) developing due to mitochondrial disease as the child is more susceptable to infections .
I would suggest you to follow the treatment as told by your doctor and keep the oral cavity clean to avoid any infections and a regular visit for every1 month or 2 months is good.
Hope i have answered your query.
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Child Suffering From Mitochondrial Disease Affecting Brain, Have Dental Problems. Are They Related?

Hi, Thank you for the query. Mitochondrial disese is a result of failure from the mitochondria, specialized compartments present in every cell of the body except RBC. when they fail, less energy is generated in the cell leading to cell injury and death of cell follows. They appear to cause most damage to cells of brain,skeletal muscles, kidney, endocrines and respiratory system leading to symptoms including loss of motor control , muscle weakness and pain,GI disorders , swallowing difficulty and poor growth, seizures,developmental delay and susceptability to infections. Yes, there is chance for the dental problems (cavities) developing due to mitochondrial disease as the child is more susceptable to infections . I would suggest you to follow the treatment as told by your doctor and keep the oral cavity clean to avoid any infections and a regular visit for every1 month or 2 months is good. Hope i have answered your query.