Get your Health question answered in 3 easy steps
A Doctor will be with you shortly
Ask a Doctor Now
157 Doctors are Online

Child has stomach pain, fever, runny nose, cough, sore ear. Labs showed high SGPT, SGOT. Reason?

Hi, my little girl first suffered from pain in the stomach , fever , cough , runny noise and sore ear. After checking with a doctor and after doing the lab test which are as follow: SGOT: 66 SGPT: 71 HPs Ag: negative HCV Ab: negative HAV IgM: negative CRP: negative H.POLORI: negative Also the urine test was normal nothing in it not normal. I wonder what might be the reason of the high SGPT & SGOT. Thanks
Asked On : Thu, 21 Feb 2013
Answers:  1 Views:  42
Report Abuse
Share on Facebook
Share on Twitter
Share on Google+
Question is related to
General & Family Physician 's  Response
Dec 2012
Hello Dear,

I understand your concern and it might be very disturbing especially after going through all the lab test and almost everything seems normal except for the liver enzymes (indicating liver failure). The symptoms and the elevated liver enzymes as you describe might signify an autoimmune hepatitis. Autoimmune hepatitis is inflammation of the liver that occurs when immune cells mistake the liver's normal cells for harmful invaders and attack them. It might occur along with other autoimmune diseases. Your doctor might need to request some tests to confirm the suspicion.

Tests for autoimmune hepatitis include:
- Anti-liver kidney microsome type 1 antibody (anti LKM-1)
- Anti-nuclear antibody (ANA)
- Anti-smooth muscle antibody (SMA)
- Serum IgG
- Liver function tests (already done, other enzymes could be tested too)
- Liver biopsy to look for chronic hepatitis

Treatment :You daughter may need prednisone or other corticosteroid medicines help reduce the inflammation. Azathioprine and 6-mercaptopurine are drugs used to treat other autoimmune disorders. They have been shown to help people with autoimmune hepatitis, as well.

Now lets not go too far. If you are in a context where malaria is endemic, then it is possible that malaria might be responsible for the above symptoms. Other parasitic or viral infections that present like malaria such as dengue fever, schistosomiasis etc needs to investigated and if they are responsible should be treated.

Hope this could be hepful
Answered: Thu, 21 Feb 2013
I find this answer helpful
Disclaimer: These answers are for your information only and not intended to replace your relationship with your treating physician.
This is a short, free answer. For a more detailed, immediate answer, try our premium service [Sample answer]


Loading Online Doctors....
© Ebix, Inc. All Rights Reserved.
All the information, content and live chat provided on the site is intended to be for informational purposes only, and not a substitute for professional or medical advice. You should always speak with your doctor before you follow anything that you read on this website. Any health question asked on this site will be visible to the people who browse this site. Hence, the user assumes the responsibility not to divulge any personally identifiable information in the question. Use of this site is subject to our Terms & Conditions
Already Rated.
Your rating:

Ask a Doctor