Antihistamines and decongestants were once prescribed regularly to help resolve middle ear fluid. Unfortunately this does not work well and should not be continued for this purpose. It IS appropriate to use them to reduce allergy
symptoms. Allergies can cause middle ear fluid and may be treated to prevent this. However, if there are no ongoing allergies the antihistamines and decongestants are not going to be helpful. The nasal spray
is essentially the same story. If ther are nasal symptoms that are being helped then the spray is useful, but not just for the middle ear fluid alone.