High grade fever
,rash, raised neutrophil
and ESR all are suggestive of bacterial infection. Raised bilirubin
level is due to inflammation of liver
As both of your kids become symptomatic at the same time it indicates same kind of infection leading to this.
Proper treatment with antibiotic with supportive measures is all that is needed to control the infection.A repeat test along with improvement in symptoms will indicate the response to treatment. It usually takes about 7-10 days for counts and s. bilirubin level to come to normal level.