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Can mottled skin on extremities, trunk be related to lupus ?

Hi. I have a 3 1/2 yr old daughter who occasionally has mottled skin on her extremities and trunks which became more pronounced after taking a bath. Sometimes it also appears even when she s not in the shower and the temperature is not cold . She s kind of irritated everytime the mottling appears. I ve been wondering if this is normal or not. My husband was recently suspected for having lupus because of her malar rash and positive lupus anticoagulants.pls. Help.thanks.
Asked On : Mon, 9 Jul 2012
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Allergist and Immunologist 's  Response
Just to recap - your daughter has malar rash, positive ACL antibodies and temperature-sensitive mottled skin on her extremities. She is very young but unfortunately of the right gender for risk of autoimmune diseases like SLE.
She needs extensive workup with full blood count (to exclude cytopenias), ANA profile, dsDNA, brain scan (if any history of fevers with fits), cryoglobulin screen with typing (if positive). Cryoglobulin is a type of protein that clots when skin temperature falls below core temperature and therefore very important to keep extremities warm at all times. You need to ensure she is reviewed by a Paediatric Rheumatologist asap.
Answered: Mon, 9 Jul 2012
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