commonly occurs in males between 20-40. Co-relation with HLA B27 is strong. I is an auto-immune disorder. For diagnosis CT Scan / MRI can be done for upper lumbar vertebrae
. Also Antineutrophil cytoplasmic antibodies
, Tumor necrosis factor-alpha
(TNF α) and IL-1 are important diagnostic tools.
Your breathlessness may be because of apical lung fibrosis
which can be checked by CT / MRI.
Schober's test can be done to note the normal increase in the distance between two fixed point while flexion of spine as compared to during straight / erect position.
Ankylosing spondylitis is sero-negative spondyloarthropathies, where RA factor would be negative.