How long does it take to have Lisinopril leave your system. I have carotid artery disease and am on Metoprolol for high blood pressure. It wasn t sufficient so my Doctor added Lisinopril. Since then I have had an irritation in the throat which makes me gag and vomit and also I have a cough which feels like I have fluid in my lungs. I also have pretty good post nasal drip which I have attributed the cough to. But that seems to be getting worse as well. I have been off the Lisinopril for a week. Is that sufficient to rule out the cause for the irritation in my throat. When I vomit, I feel like I am going to have a stroke.