Hi ! There are many opinions on how people react or feel to the temperature changes with a metal in the body. Titanium is known to cause less discomfort in cold
than any steel rod, but after all it is a metal, and there may be some temperature changes towards lower side in the winter below 0 degrees even if the body temperature may try to maintain the temperature to an optimum level. In an air conditioning , the temperature you maintain is as per your own comfort zone, and so you can not predict how the metal will behave in a temperature below 0 degree. If I would be you, I possibly would try to experience it in gradual decreasing temperature to be sure about the tolerance in low temperature. So take care.