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Dr. Andrew Rynne
MD
Dr. Andrew Rynne

Family Physician

Exp 50 years

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Can Effexor Xr And Crestor Be The Cause Of Increase In Liver Enzymes ?

Been on Effexor xr, for 5 years crestor 10 mg for 3 years recently changed to Zoloft 50mg and I also take clonazepam 1mg 2x a day exercise high impact aerobics 6 times a week am 53 and recent alt of 102 and ast of 60 what may have caused increase of enzymes
Fri, 10 Jan 2014
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Dermatologist 's  Response
Dear Friend.

Yes , Crestor being a statin can cause rise in liver enzymes.
But we should rule out the other cause of raised ALT/AST.

Common causes are :
1. Alcoholic Liver disease
2. Viral Hepatitis
3. Drug Induced

I advise you following tests :
1. Liver Function Test (complete)
2. HbsAg
3. Anti HCV antibody.

Once , we know the cause we can treat it. If no other cause is found , we can implicate this to Crestor.
You should discuss with your doctor regarding substituting it.
Good Luck

Good Luck.
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Can Effexor Xr And Crestor Be The Cause Of Increase In Liver Enzymes ?

Dear Friend. Yes , Crestor being a statin can cause rise in liver enzymes. But we should rule out the other cause of raised ALT/AST. Common causes are : 1. Alcoholic Liver disease 2. Viral Hepatitis 3. Drug Induced I advise you following tests : 1. Liver Function Test (complete) 2. HbsAg 3. Anti HCV antibody. Once , we know the cause we can treat it. If no other cause is found , we can implicate this to Crestor. You should discuss with your doctor regarding substituting it. Good Luck Good Luck.