Dronis is a combined oral contraceptive pill
containing the estrogen ethinyl estradiol
and the new progestin Drospirenone
which has an additional antiandrogenic action (devoid of androgenic side effects like weight gain & acne). Azithromycin is a macrolide antibiotic, very effective & does not cause drug interactions like other macrolide antibiotics eg., erythromycin, clarithromycin
etc., Some antibiotics like amoxycillin & tetracycline inhibit deconjugation of oral contraceptives & can lead to contraception
failure. But azithromycin is safe. Still, to be on the safer side, additional contraceptive precaution should be taken while on it and also for 7 days after stopping as it has extensive tissue distribution & also because it is an erythromycin analog.