Hi,Dear,Thanks for your query to HCM. Dear I read facts of your query and reviewed it in context to your query health issues. I understood your health concerns and feel Concerned about them. Based on the facts of your query the reply of your query is- Yes,Axiron does lead to nausea. But in the absence of other information,I would suggest you to go for Physician Consults.As the facts could be different from what you submitted. So looking in to the sensitive complaint of yours,I would suggest you to rule out-GI and other causes by Consulting and investigating with Physician. It would be prudent to have physical Check from Consulting Physician before planning further investigations and treatment for it. Other causes need to be ruled out in any case. Do s -suggested for your case- Check with Family Physician and thereafter with Consulting Physician if need be Tab PPI-Penaprazole -1 x at 6 Pm would reduce nausea. Just don t worry and be patient and co-operate with your doctors,till you verify with your attending doctors. . -Other causes need to be verified with your family GP doctor and with Specialist doctors, as the facts may be different what you submitted. -For this Second opinion from PCP-or Gp doctor and if need be with Physician-is needed who would do proper investigation after proper physical assessment to resolve your health issues. -for early recovery-please follow above do s which would resolve your complex health issues. Hope this would help you to treat your health issues in the best way possible. Welcome for any further query in this regard. Good Day!! Dr.Savaskar M.N. Senior Surgical Specialist M.S.Genl-CVTS