Hello Doctor, my son Dishang, 25 yrs old had a head and cervical spine injury (C4 and C5 contusion edema ) involving bladder and bowel, after a road accident on 01/04/2012. Head injury was limited to scalp tear alone and no brain injury involved. He was treated with Solumedrol IV for the first one week and then apart from other medications with Wysolone 10 mg tablets from 08/05/2012 (for a week with 4 tablets and to be reduced one tablet, each week). He is wearing indwelling catherter since 01/04/2012, as he doesn t have the sense to expel urine. On 20/05/2012 he had sever chills, very high fever and extremely low blood pressure. He was hospitalised and was initially tought to be UTI but later confirmed by blood culture reports as Septicemia involving Klebsiella bacteria. He is being treated with antiboitcs. His BP is normal, after initial medications on day one. However after two days, his Creatinine level had raised to 1.9 mg/dl and his platelet counts dropped to 0000. He had slight nasal bleeding on 24/05/2012, so he was infused with 4 units of platlets on 24/05/2012 and today morning s platelet count shows 0000. No nasal bleedings observed. His Creatinine as of this morning is 1.7 mg/dl. Althrough these days he had on and off fever with temperatures of 99 to 100 deg F. However since last evening, his temperature has rised to 103 deg F. His heartbeat is 100/min. Doctor, in his case isn t the antiboits working against Klebsiella due to previous usage of Wysolone? Why doesn t his temperature and heart beat doesn t come to normal levels. What further treatment can be done for this patient? Please advise.