Hello and welcome to HCM
The presence of chronic itching is definately a predisposing factor for development of squamous hyperplasia
and subsequently intra-epithelial lesion.
For your understanding, vulval skin is covered by a layer of stratified squamous epithelium
which is several layer thick. The lower most layer is called thae basal layer and is separated from the underlying stroma by a basement membrane.
VIN 1 (Vulvar intraepithelial lesion 1) is characterised by atypical features in the lower one third of the stratified squamous epithelium.
If the lesion is not removed and left in place for years, VIN 1 may progress to VIN 2, VIN3 and finally invasive squamous cell carcinoma
Invasive squamous cell carcinoma is a malignant entity in which the atypical cells penetrate the basement membrane and invade the stroma.
Removal of the lesion was the best treatment option but a regular follow up is required.
Refarding your query regarding HPV
, you can get HPV PCR done to find out the HPV status. If positive appropriate treatment can be started. If negative follow up will suffice.
VIN 1 is a low grade lesion so chances of developing VIN 2, 3 and invasive carcinoma are low.
Thanks and take care
Dr Shailja P Wahal