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Dr. Andrew Rynne
MD
Dr. Andrew Rynne

Family Physician

Exp 50 years

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Been Taking Epilim And Neurontin For Left Temporal Lobe Epilepsy, Hypothyroidism, Lethargic, High TSH Levels. Medication?

Hello I am a 44 year old woman, have been taking Epilim and Neurontin for Left temporal lobe epilepsy for some years. I have recently been diagnosed with Hypothyroidism and am wondering if these medications can contribute to this condition and my weight gain. I have tried diets and exercise to no effect, constantly feel tired and lathargic. I have also had a hysterectomy when I was 30.. I am having hot flashes also. I have high TSH levels but normal T3 T4 levels. Could these medications contribute to my Hypothyroidism as well as maybe having a very early hysterectomy contribute to my hypothyroidism. Your opinion would be helpful. Thank you. Tania.
Wed, 26 Dec 2012
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General & Family Physician 's  Response
Hello,
Epilim is sodium valproate and Neurontin us Gabapentin. These drugs are useful in epilepsy and various other conditions. Like every drug, these drugs also have some common side-effects and some rare ones. However these drugs causing hypothyroidism is not known popularly. Secondly, hypothyroidism is very common among the ladies in 30s and 40s and all the symptoms mentioned by can be explained by hypothyroidism. Though you have normal T3 and T4, raised TSH warrants treatment for hypothyroidism. Your hysterectomy may not have much to do with your current problems. Hot flushes which you have described can be a sign of menopause. Please visit a physician and start your drugs for thyroid supplementation. Your response to these drugs will also be an indicator for hypothyroidism.
Hope I am able to solve your concerns.
Thanks. Get well soon.
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Been Taking Epilim And Neurontin For Left Temporal Lobe Epilepsy, Hypothyroidism, Lethargic, High TSH Levels. Medication?

Hello, Epilim is sodium valproate and Neurontin us Gabapentin. These drugs are useful in epilepsy and various other conditions. Like every drug, these drugs also have some common side-effects and some rare ones. However these drugs causing hypothyroidism is not known popularly. Secondly, hypothyroidism is very common among the ladies in 30s and 40s and all the symptoms mentioned by can be explained by hypothyroidism. Though you have normal T3 and T4, raised TSH warrants treatment for hypothyroidism. Your hysterectomy may not have much to do with your current problems. Hot flushes which you have described can be a sign of menopause. Please visit a physician and start your drugs for thyroid supplementation. Your response to these drugs will also be an indicator for hypothyroidism. Hope I am able to solve your concerns. Thanks. Get well soon.