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Dr. Andrew Rynne
MD
Dr. Andrew Rynne

Family Physician

Exp 50 years

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Been On Lisinopril. Can That Result In Itchiness All Over Body? What Can Help?

I ve been on Lisinopril 10mg now for about 1.5yrs. Just recently my doctor suggested cutting it in half and maybe even off completely. I started that process and after about 3 weeks at half dosage I was itchy all up and down my arms and my face and body felt like I was radiating heat. So i went back to the 10mg dosage. All seemed to go away. So i started the reduction again. Again after about 2 weeks at half dosage the itcyness and radiant heat have come back. is this normal? Should I press through this and all will go away in time or what do you think?
Mon, 23 Sep 2013
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Internal Medicine Specialist 's  Response
Hi,
Thanks for posting your query.
The lisinopril belongs to ACE inhibitor group of antihypertensive.
It can affect the metabolism of smaller hormones in the body. Their levels increase particularly the levels of histamine, which can be cause of itching and cough in a fraction of patients.
In such cases the drug should be stopped and another class of drugs called ARBs should be used in it's place.
Hope I have answered your query.
If you have any questions I will be happy to answer.
Please close the query if you have no other questions.
Wish you a good health.
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Been On Lisinopril. Can That Result In Itchiness All Over Body? What Can Help?

Hi, Thanks for posting your query. The lisinopril belongs to ACE inhibitor group of antihypertensive. It can affect the metabolism of smaller hormones in the body. Their levels increase particularly the levels of histamine, which can be cause of itching and cough in a fraction of patients. In such cases the drug should be stopped and another class of drugs called ARBs should be used in it s place. Hope I have answered your query. If you have any questions I will be happy to answer. Please close the query if you have no other questions. Wish you a good health.