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Dr. Andrew Rynne
MD
Dr. Andrew Rynne

Family Physician

Exp 50 years

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Are Abdominal Pain, Enlarged Spleen And Itching Symptoms Of Lymphoma?

Dear Doctor,

My name is nedal, I’m 42 male.

My problem started back in 2007, since then I was looking for an answer to my question: do I have lymphoma?????.

In 2007 i had abdominal ultrasound, my spleen was enlarged (14.7 cm), I had itching, night sweats and joint pain. H.pylory test was positive, high uric acid.

In 2009 i had another abdominal ultrasound, my spleen was (15 cm), all other symptoms were there

In 2010 I discovered that I had 2 lymph node swollen in my neck. One of them was removed (biopsy) and examined, the final result was no morphological and immunohistochemical evidence to support the diagnosis of lymphoma and we advice for follow up.

The second lymph node disappears after antibiotic.

In 2011 I had a third abdominal ultrasound, my spleen was (15.2 cm), all other symptoms were there. I consulted a doctor, he asked for some blood tests:

CBC, ESR, CRP, B2- macroglobulin, LDH, Serum protein electrophoresis and , Immunoglobulin levels, Al came back normal.



My question: is it possible for someone to have all of the above symptoms which is specific to lymphoma and still have no lymphoma?

On the other hand is it possible for someone to have a biopsy and all these blood test which is normal (from 2007 to 2011) and still have lymphoma?

Mon, 27 Jul 2015
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Radiologist 's  Response
Hi,
Thanks for writing in.

You might have encountered reactive enlargement of lymphnode sue to infection. This is the reason one of them disappeared after antibiotic.

Spleen enlargement might be seen in many disorders and you do not seem to have a lymphoma if your spleen is enlarged for years.

Lymphoma is a diagnosis that is strongly supported by biopsy and immunohistochemistry. Since you have got it done therefore lymphoma is less likely.

Please do not worry and it is confirmed that you do not have lymphoma.
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Are Abdominal Pain, Enlarged Spleen And Itching Symptoms Of Lymphoma?

Hi, Thanks for writing in. You might have encountered reactive enlargement of lymphnode sue to infection. This is the reason one of them disappeared after antibiotic. Spleen enlargement might be seen in many disorders and you do not seem to have a lymphoma if your spleen is enlarged for years. Lymphoma is a diagnosis that is strongly supported by biopsy and immunohistochemistry. Since you have got it done therefore lymphoma is less likely. Please do not worry and it is confirmed that you do not have lymphoma.