Hi.. As you said you are having acne vulgaris for long time. I would like to say something about acne.There may be different forms of acne..like white comedones,black comedones,inflammatory acne, conglobet and cystic acne . Acne vulgaris is a multifactorial disease. Hereditary factor may there. There may be some cause. Stress,anxiety,oily food,dandruff, sleeplessness, hormonal imbalance,drugs like pills,steroid ..etc may cause or exacerbate the disease. Oral drugs along with topical applications might improve the lesions.You consult dermatologist. I advise in my patients having acne as below.. - to avoid all suspected factors which stimulate or exacerbate the lesions - tab azithromycine 500 mg thrice a week 24 hourly consecutively for few months Or cap minocycline 50 mg daily in the morning. - tab isotretinoin 5 mg in low dose daily at night - clindamycine gel, benzoyl peroxide or adapalene gel to apply at night on lesions only -cleanse the face with antiseptic face wash like acmed or acwash face wash Have patience as the good result may be there after few months. And relapse may be prevented. Be positive and remain happy for the good result.I hope you got my answer. Thanks. Dr. Ilyas Patel MD