Hello dear I understand your concern PCOS is complex disease and treatment response is variable. It cause hormonal imbalance, menstrual irregularity, insulin resistance and weight gain. All these factors cause female infertility. Both glucopahse, duphaston and clomid will help to become pregnant. Glucopahse: decrease insulin resistance and induce ovulation Dupahston: regularize hormone imbalance, support implantation and early pregnancy. Clomid : increase ovulation in 80% case and increase fertility by 50%. After taking clomid go for USG scan and ovarian follicle study to know response of treatment. If ovarian follicle size will be between 18-21 mm then it will release best quality egg and high chance of pregnancy. You should use above treatment for 4-6 months to become pregnant. You can also use HCG injection if ovulation will not occur and ovacare pill Avoid stress, take healthy diet, drink plenty if water and do regular exercise Hope this may help you Contact further if follow up needed Best regards Dr. Sagar