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Abscesses in diabetic patients are common, and pitting edema is solely not a sign of gangrene
. Changes in the skin of the affected area are usually the first sign of gangrene. The skin may pale as a result of the decrease in blood flow. The color may quickly redden or darken. As gangrene advances, the skin of the affected area turns a very dark green to black color. A discharge with a foul odor develops as tissue death spreads. This discharge occurs whether or not there is an associated wound. There may also be blisters filled with the discharge. Gangrene causes severe pain
or pressure; however, in diabetics with significant nerve damage
in the affected area, there may be no sensation of pain.