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Abnormality of insertion of short arm segment between bands 12p11.2 and 12p13 into the long arm at band 12q24.3. What does this mean?

Hi, may I answer your health queries? Please type your query here... Abnormality of insertion of short arm segment between bands 12p11.2 and 12p13 into the long arm at band 12q24.3
Asked On : Wed, 22 Feb 2012
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Internal Medicine Specialist 's  Response
Dear friend, welcome to Healthcaremagic!
I am Dr. Prasad Akole (Critical Care Expert- http://bit.ly/Dr-Prasad-Akole) and am glad to address to your query here.

Many genetic conditions are related to changes in particular genes on chromosome 12. Changes in the structure or number of copies of a chromosome can also cause problems with health and development. Many blood cancers and tumours are related to such changes.

‘Abnormality of insertion of short arm segment between bands 12p11.2 and 12p13 into the long arm at band 12q24.3’ indicates a genetic defect in the structure of chromosome 12 bands.

You may find the following resources about chromosome 12 helpful. These materials are written for the general public.
Additional NIH Resources - National Institutes of Health
National Human Genome Research Institute: Chromosome Abnormalities

I hope to have answered your query satisfactorily. I would be glad to answer any further queries. Take care and please keep me informed of your progress at http://bit.ly/Dr-Prasad-Akole
Good Luck!
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Answered: Sun, 28 Apr 2013
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