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Normally if there is no associated illness heart attack
is not common in females at 25 yrs or even till menopause
and the main reason is estrogen
acts as a protector of the heart in females.The symptoms your wife is describing may be of anxiety
but if you do not rule out heart problem by taking out a ECG at a ER her anxiety will increase.Also her weight is a factor which can be a cause for heart attack at least she will feel so.Please get her to a ER and get a ECG done if the ECG is normal then you can assure her and she will also relax as there is no heart problem.