Brief Answer: Ask ur doctor to prescribe treatment advised by me Detailed Answer: Hi dear, Thanks for your query. I fully understand the concerns for your problems and frustrations over the so-called indifferent doctors. I have gone through the details very carefully, based on which I have short-listed the following problems you are suffering from :- 1. Chronic mental stress/anxiety with underlying mild depression(feeling of cold, sleeplessness, foggy brain, loss of appetite) 2. GERD (Gastro-Esophageal Reflux Disease) with possible H.pylori infection of the stomach + intestine ( loss of appetite, upper abdominal pain, tendency to sleep in upright position, sore throat + headache which wakes you up from sleep: sore throat is apparently due to reflux of stomach acid to the mouth; chronic pain overlying the colon. 3. IBS (Irritable Bowel Syndrome) :- features of anxiety, upper abdominal + colonic pain, mild/moderate constipation, recurrent abdominal discomfort, 3. Scoliosis-induced band-like pain around the back/shoulders. I strongly feel that- in addition to the blood tests already done- you should undergo the following tests :- * Colonoscopy to directly visualize the inside of the colon for diverticula, polyps, growth or, inflammation of inner lining of colon. * Endoscopy to directly visualize the condition of the stomach/duodenal lining (for inflammation, erosions and ulcers). * Breath test and stools examination for H.pylori infection * Blood Vitamin B12 and D, Folic Acid, Calcium levels to estimate the deficiency. In my vast 35 years of clinical practice, I have seen and treated hundreds of similar cases, with a high success rate. Hence, if I were your treating specialist, I would have advised the following treatment:- (a) A long term (6-12 months or even more, if required) of a combination of # an anti-depressant, such as, Sertraline or Escitalopram # An anti-anxiety drug, such as, clonazepam or alprazolam (b) 2 weeks' course of Anti-H.pylori therapy + Pro-kinetic drug, such as, Metoclopramide; FOLLOWED BY (w.e.f. Day 15) # 3-4 months' course of - Proton Pump Inhibitors (PPIs), such as, Rabeprazole or Esmoprazole - Probiotic drug, such as, Lactobacilli thrice daily - Digestive enzymes thrice daily - Psyllium husk/granules/powder twice daily - Daily supplements of Vitamin B12 (Mecobalamin) 1.5mg + Vitamin D3 (Calcitriol) 0.5micrograms + Folic acid 5mg + Calcium Carbonate 1gm/day # A single-tablet of Albendazole (400mg) on Day 1, repeat after 3 days. Scoliosis has apparently caused disc(s) protrusion/herniation or narrowing of the spinal canal. Consult a Neurosurgeon for diagnosis/exclusion of these conditions. Consult your doctor and apprise him of my opinion. I am certain that he will agree with me; order required tests, and- will prescribe suitable treatment as advised, in appropriate/effective doses. Hope I have addressed to your concerns to your complete satisfaction and you find my response helpful and informative. I will be happy to answer further queries, if any. Take care & JUST RELAX: HAVE FAITH IN ME AND YOURSELF. YOU W-I-L-L BE ALL RIGHT IN NEAR FUTURE. Col (Dr.) Rakesh Karanwal

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Brief Answer: Anti-H.pylori therapy required for maximum benefit Detailed Answer: The root cause of your problems is apparently H.pylori infection. You are UNLIKELY to have much relief with vitamins, enzymes and supplements UNLESS you treat the root cause. Take a course of anti-H.pylori therapy SIMULTANEOUSLY, in order to get maximum benefit. Take care

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