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What Is The Reason For Increasing The Dosage Of Thyronorm During Pregnancy?

Posted on Thu, 26 Dec 2013

Question: Is the below mentioned dosage during 1st trimester is appropriate: 7-8th Week: Thyronorm 75mcg for 5 days, Thyronorm 50mcg for 2 days 9-10thWeek:Thyronorm 75mcg for 6 days, Thyronorm 50mcg for 1 day 11-12thWeek:Thyronorm 75mcg for all 7 days. Currently my Free T4 and TSH are within the range then why I as asked to increase the dose as mentioned above.

Answered by Dr. Manoranjan Chowhan (5 hours later)

Brief Answer: Reply Detailed Answer: In pregnancy there may be higher requirement of Thyronorm as it's very important to keep the patient normothyroid the dose of Thyronorm needs to be adjusted to achieve the same. Thyroxine requirements increase by 25-30% during pregnancy with increased requirements seen as early as the fifth week of pregnancy. Children born to women whose hypothyroidism was inadequately treated in pregnancy are at increased risk of neuropsychological impairment. There fore there is requirement of augmented dose as prescribed by your Doctor however periodic monitoring of Free T4 and Sr TSH is important too. with best wishes and thanks from Dr Chowhan

Above answer was peer-reviewed by : Dr. Yogesh D

Follow up: Dr. Manoranjan Chowhan (9 hours later)

Does that mean that based on my current TSH value there is a need to increase the Thyronorm dose every 2 weeks once.

Answered by Dr. Manoranjan Chowhan (5 minutes later)

Brief Answer: Reply Detailed Answer: The dose has to be augmented keeping in view your current TSH level and the requirement in first trimester. Hope the dose increase was suggested by an Endocrinologist; if so please follow his/her advice. As regards monitoring the dose is concerned it is always beneficial to keep track and monitor by regular TSH assay. with best wishes Dr Chowhan

Above answer was peer-reviewed by : Dr. Prasad

Follow up: Dr. Manoranjan Chowhan (11 minutes later)

My next test is advised to e taken after 6 weeks. Yes it is suggested by Endocrinologist whereas my Gynic dint not suggest me any increase of dosage.

Answered by Dr. Manoranjan Chowhan (12 hours later)

Brief Answer: Reply Detailed Answer: You should follow advice given by your treating Endocrinologist as they are aware about this important issue of dose adjustment keeping in mind your first trimester of pregnancy. with best wishes Dr Chowhan

Note: For more information on hormonal imbalance symptoms or unmanaged diabetes with other comorbid conditions, get back to us & Consult with an Endocrinologist. Click here to book an appointment.

Above answer was peer-reviewed by : Dr. Vaishalee Punj