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What Is Survival Rate For Colon Cancer?

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Posted on Tue, 17 Feb 2015
Question: What is approx survival for colon cancer . Surgery was march 2014 to remove primary. Recent can show
1 liver met, 1 aortocaval node, 1 subpleural nodule of under 1 cm
Chemo so far not worked - xeloda , irinotecan .

What else can be done . Can ablation be done?
doctor
Answered by Dr. Dr. Ivan Romich (3 hours later)
Brief Answer:
Survival rate is hard to determine

Detailed Answer:
Hi,

Thanks for your query.

Considering those metastatic lesions, it was obviously Dukes C colon cancer amd now this is advanced stage of malignant disease. Surgery in cases of multiple metastases has not any role and only hope in such cases is to start with chemotherapy which may kill lymph nodes metastases and then this one in liver can be surgically removed.

If chemo dont take effect,unfortunately, further treatment is limited. Ablation and other percutaneous intervention can be done to manage liver met but it is useless for lymph nodes metastases. in this case liver met is not worrying since it will grow slowly and progression of the disease will come form paraaortal lymph nodes. You should start with 2nd and 3 rd line of chemo or with experimental therapy if you can find some. 5 year survival in these cases is less than 5%. 1 year survival is approx. 50% , 2 years 25-30%. 3 and more can be expected in only cca 10% of people.

Regards,
Above answer was peer-reviewed by : Dr. Raju A.T
doctor
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Follow up: Dr. Dr. Ivan Romich (1 hour later)
They gave irinitecan which obviously didn't work.they started with folfiri but after 1 session they was chest tightness so was stopped .

They can't give anymore 5 fu chemo they said .

A radiologist can do something called nano knife ok all mets , should we go got it ?
doctor
Answered by Dr. Dr. Ivan Romich (11 minutes later)
Brief Answer:
May not be useful

Detailed Answer:
Hi,

I am not sure that nano knife can kill paraaortal metastases. it can affect liver mets and it is used for it in most cases but if other 2 secondary lesions cant be completely destroyed,then there is no purpose of treating liver mets with nanoknife when these liver lesions can be treated by other more conventional methods: surgery, chemoembolisation,etanol injection or electrocoagulation.
If radiologist think that all metastases can be successfully treated by nanoknife then you can try with it but chemotherapy should be continued if you ask me

Regards,
Above answer was peer-reviewed by : Dr. Raju A.T
doctor
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Follow up: Dr. Dr. Ivan Romich (1 hour later)
We are seeking a second opinion . Do u agree ? As my dad at present has 3 mets , people with 10/20
Even get diff chemo tried. We were thinking ablate these and chemo .

If nano knife can ablate all 3 is it worth it. ?

doctor
Answered by Dr. Dr. Ivan Romich (12 hours later)
Brief Answer:
Yes, It will if patient is in good health.

Detailed Answer:
Yes, it definitely is especially if patient is in good health and have motivation for aggressive but efficient treatment. Nano knife radiation should be combined with chemotherapy. It may have significant systemic side effects but this is only way to achieve long term survival. At this point it is more important to see effect of nano knife on paraaortal lymph nodes and subpleural node and if there is good result then the same can be done for liver met or liver met can be surgically removed.

Experience with nano knives is limited but in some people there is very good response and if you have available nano knife then you should go for it.
Above answer was peer-reviewed by : Dr. Ashwin Bhandari
doctor
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Follow up: Dr. Dr. Ivan Romich (5 hours later)
Thx . 1 hospital only here in uk does it . He reviewed images N says my father can have it so we should right ?

Will ablating these enable him to live long like 3/4 years you think ?
doctor
Answered by Dr. Dr. Ivan Romich (40 minutes later)
Brief Answer:
Yes,

Detailed Answer:
Hi,

Yes,this is something that you can hope for although it is hard to predict tumor growth dynamics. at this point lesions are very small and it may take years till it infiltrate vital organs...

Regards,
Above answer was peer-reviewed by : Dr. Raju A.T
doctor
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Follow up: Dr. Dr. Ivan Romich (1 hour later)
Thx so much my last query is , the issue comes in when they start infiltrating viral organs right. ? Do they have to be big and very many for this to happen ?

Can the mets suddely start appearing and growing very fast ?
doctor
Answered by Dr. Dr. Ivan Romich (15 hours later)
Brief Answer:
hi

Detailed Answer:
yes, the main problem may be if tumor infiltrate duodenum,small intestines and cause obstruction. or if liver met infiltrate main billiary ducts and cause jaundice. it is hard to say when or will it happen,but usually tumors must be larger than 10 cm to cause it or it must be located near these important organs. In every case,if it cant be completely cured, then it definitely can be slowed down by chemo or radioth. Of course, complete cure isnt impossible and about 5% of people may be cured. The dynamics of mets growth is variable,but in most cases it doesnt occur suddenly and grow relatively slow. Only mets on small intestines and parietal peritoneum called carcinosis, show rapid progression. Liver and lympoh nodes mets are less progressive, but it would be best to repeat ct scan in 2-3 months an deverything will be clear. I really hope that treatment will show some good results. Be patient and believe in it. Wish you good luck and good health.
Note: For further queries related to kidney problems Click here.

Above answer was peer-reviewed by : Dr. Vaishalee Punj
doctor
Answered by
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Dr. Dr. Ivan Romich

General Surgeon

Practicing since :2008

Answered : 13886 Questions

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What Is Survival Rate For Colon Cancer?

Brief Answer: Survival rate is hard to determine Detailed Answer: Hi, Thanks for your query. Considering those metastatic lesions, it was obviously Dukes C colon cancer amd now this is advanced stage of malignant disease. Surgery in cases of multiple metastases has not any role and only hope in such cases is to start with chemotherapy which may kill lymph nodes metastases and then this one in liver can be surgically removed. If chemo dont take effect,unfortunately, further treatment is limited. Ablation and other percutaneous intervention can be done to manage liver met but it is useless for lymph nodes metastases. in this case liver met is not worrying since it will grow slowly and progression of the disease will come form paraaortal lymph nodes. You should start with 2nd and 3 rd line of chemo or with experimental therapy if you can find some. 5 year survival in these cases is less than 5%. 1 year survival is approx. 50% , 2 years 25-30%. 3 and more can be expected in only cca 10% of people. Regards,