Brief Answer: Don't drive, don't operate heavy machinery Detailed Answer: Hi! Thanks for coming to HealthCareMagic. I'm pretty sure you are aware that both the drugs can make you drowsy and I am glad you are taking the precaution of checking. In my experience, a relatively healthy person who has not liver or kidney problems can take the two medications in those doses without danger, But you will be knocked out like a light! Be careful, do not handle sharp objects, drive a car or handle any heavy machinery. So if you are sure that you won't be doing anything that requires alot of coordination or thinking, you could take the Benadryl. Take care and I hope you get a good nights sleep. Feel free to follow-up for this or anything else. Thanks again for coming to HealthCareMagic.com

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