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What Does My Lab Test Report Indicate?
Question: IMPRESSION:
No acute intracranial abnormality or mass effect. The visualized cavernous
sinuses, Meckel's caves, and trigeminal nerves are unremarkable on this
unenhanced study.
Scattered foci of T2 prolongation in the periventricular and deep white matter
are nonspecific. Differential considerations include sequelae of migraines,
demyelinating or other inflammatory processes, or chronic microvascular
changes.
No acute intracranial abnormality or mass effect. The visualized cavernous
sinuses, Meckel's caves, and trigeminal nerves are unremarkable on this
unenhanced study.
Scattered foci of T2 prolongation in the periventricular and deep white matter
are nonspecific. Differential considerations include sequelae of migraines,
demyelinating or other inflammatory processes, or chronic microvascular
changes.
Brief Answer:
MRI brain report interpretation
Detailed Answer:
Hi xxxxxxxxxxxxxxxxxxxxx, thanks for asking from HCM.
I can understand your concern. You have provided a MRI brain report here. According to this report, the patient's brain is almost ok i.e. no tumor, no vascular malformation, no bleed, no hydrocephalus. The different cranial structures like cavernous sinus, trigeminal nerves are ok.
Now coming to the positive finding - It says some periventricular and deep white matter multiple T2 lesions, small and scattered. As per report, there are differential diagnosis like sequelae of migraines, demyelinating or other inflammatory processes, or chronic microvascular changes.
To confirm the diagnosis or find the relevance, we need to know following points
- Age - Usually old age like more than 60 years, it can be microangiopathic ischemic stroke changes, microvascular changes.
In young age like 20-40 years, these white matter changes are mostly due to demyelinating diseases like multiple sclerosis, leucodystrohy
- Clinical findings - Findings like increased fatigue, poor vision, muscle fibrillations point towards diagnosis of multiple sclerosis. While forgetfulness, behavioural changes, incontinence point towards chronic ischemic infarcts.
- Blood workup - Increased serum homocysteine level, increased cholesterol level, diabetes mellitus usually cause chronic ischemic changes.
While positive antibody tests point towards demyelinating disorder.
So you should provide some information about the patient or consult a neurologist. He will examine the patient, correlate clinically and might advise few more investigations to confirm the disease.
Hope it will help you. If still any doubt, do let me know.
Thanks. Take care.
MRI brain report interpretation
Detailed Answer:
Hi xxxxxxxxxxxxxxxxxxxxx, thanks for asking from HCM.
I can understand your concern. You have provided a MRI brain report here. According to this report, the patient's brain is almost ok i.e. no tumor, no vascular malformation, no bleed, no hydrocephalus. The different cranial structures like cavernous sinus, trigeminal nerves are ok.
Now coming to the positive finding - It says some periventricular and deep white matter multiple T2 lesions, small and scattered. As per report, there are differential diagnosis like sequelae of migraines, demyelinating or other inflammatory processes, or chronic microvascular changes.
To confirm the diagnosis or find the relevance, we need to know following points
- Age - Usually old age like more than 60 years, it can be microangiopathic ischemic stroke changes, microvascular changes.
In young age like 20-40 years, these white matter changes are mostly due to demyelinating diseases like multiple sclerosis, leucodystrohy
- Clinical findings - Findings like increased fatigue, poor vision, muscle fibrillations point towards diagnosis of multiple sclerosis. While forgetfulness, behavioural changes, incontinence point towards chronic ischemic infarcts.
- Blood workup - Increased serum homocysteine level, increased cholesterol level, diabetes mellitus usually cause chronic ischemic changes.
While positive antibody tests point towards demyelinating disorder.
So you should provide some information about the patient or consult a neurologist. He will examine the patient, correlate clinically and might advise few more investigations to confirm the disease.
Hope it will help you. If still any doubt, do let me know.
Thanks. Take care.
Above answer was peer-reviewed by :
Dr. Remy Koshy
My Mother has MS. Is MS hereditary?
Brief Answer:
MS is hereditary
Detailed Answer:
Hi xxxxxxxxxxxxxxxxxxxxxx, welcome back.
MS was considered to be non hereditary, but increased risk in siblings has been seen. Etiology of MS is still not clear. It is considered to be due to viral infection followed by autoimmune antibody formation.
However new study by Prof. Carles Vilariño-Güell.multiple reported that Multiple sclerosis can result from a single genetic mutation on a gene called NR1H3. This, they say, produces a protein that acts as an “on-off switch” for other genes. So it can pass from parents to children.
Hope it will clear your doubt. If still any doubt, do let me know.
Thanks. Take care.
MS is hereditary
Detailed Answer:
Hi xxxxxxxxxxxxxxxxxxxxxx, welcome back.
MS was considered to be non hereditary, but increased risk in siblings has been seen. Etiology of MS is still not clear. It is considered to be due to viral infection followed by autoimmune antibody formation.
However new study by Prof. Carles Vilariño-Güell.multiple reported that Multiple sclerosis can result from a single genetic mutation on a gene called NR1H3. This, they say, produces a protein that acts as an “on-off switch” for other genes. So it can pass from parents to children.
Hope it will clear your doubt. If still any doubt, do let me know.
Thanks. Take care.
Above answer was peer-reviewed by :
Dr. Remy Koshy
Answered by
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