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What Does My Endoscopy Result Suggest?
Question: Good Morning Sir,
In the recent endoscopy of my anti, some fundal polyps were found and removed.
Sample of Polyps was send for Biopsy and it diagnosed Neuroendocrine Tumor.
Other test were also done like PET Scan, Ga Dotanoc whole body pet ct Scan the results were negative.
Currently she is giving Octreotide injection daily.
That injections are having many side effects as said by doctors.
Sir Please suggest for further Treatment.
Thanks & Regards.
In the recent endoscopy of my anti, some fundal polyps were found and removed.
Sample of Polyps was send for Biopsy and it diagnosed Neuroendocrine Tumor.
Other test were also done like PET Scan, Ga Dotanoc whole body pet ct Scan the results were negative.
Currently she is giving Octreotide injection daily.
That injections are having many side effects as said by doctors.
Sir Please suggest for further Treatment.
Thanks & Regards.
Brief Answer:
octreotide monotherapy
Detailed Answer:
Hi
Since your auntys biopsy report came out to be Neuroendocrine Tumor it has to be treated with octreotide monotherapy.
Treatment with octrotide injection is dosed 20 to 30 mg and can be given intramuscularly every 14 to 28 days.
Median time to tumour progression improved with octreotide treatment and was about 14.3 months.
Some targeted agents such as interferon alpha have indicated responses when used in combination with octreotide and in some patients previously treated with chemotherapy.
Chemotherapy agents doxorubicin, fluorouracil, dacarbazine and streptozocin have shown to have limited activity in this disease.
Side effects of octrotide injection like nausea, vomiting, loose stools, constipation, stomach upset, or gas needs to be managed symptomatically by your doctor.
After completion of 4 cycles of this injection i would suggest u repeat a PET scan.
Regards
DR De
octreotide monotherapy
Detailed Answer:
Hi
Since your auntys biopsy report came out to be Neuroendocrine Tumor it has to be treated with octreotide monotherapy.
Treatment with octrotide injection is dosed 20 to 30 mg and can be given intramuscularly every 14 to 28 days.
Median time to tumour progression improved with octreotide treatment and was about 14.3 months.
Some targeted agents such as interferon alpha have indicated responses when used in combination with octreotide and in some patients previously treated with chemotherapy.
Chemotherapy agents doxorubicin, fluorouracil, dacarbazine and streptozocin have shown to have limited activity in this disease.
Side effects of octrotide injection like nausea, vomiting, loose stools, constipation, stomach upset, or gas needs to be managed symptomatically by your doctor.
After completion of 4 cycles of this injection i would suggest u repeat a PET scan.
Regards
DR De
Above answer was peer-reviewed by :
Dr. Vaishalee Punj
Sir
Is there any other treatment available rather than injections like any medicine/ surgery etc.
Because now she is admitted in hospital and once after discharge, it will be difficult to provide injections as per schedule and to track for any side effects.
How danger it is ?
Is there is any chance of that may be converted in cancers cell ( carcinoid)?
Is there any other treatment available rather than injections like any medicine/ surgery etc.
Because now she is admitted in hospital and once after discharge, it will be difficult to provide injections as per schedule and to track for any side effects.
How danger it is ?
Is there is any chance of that may be converted in cancers cell ( carcinoid)?
Brief Answer:
surgical oncologist
Detailed Answer:
Hi
Since your auntys neuroendocrine tumour has not spread to the liver in the PET scan and if the tumor is less than 2 cm with up to 6 polyps then it can be resected endoscopically, with subsequent interval follow-up.
If the tumors are measuring more than 2 cm with more than 6 polyps, then local surgical resection is recommended.
About 10 % of patients with neuroendocrine tumour are converted to carcinoid which can cause carcinoid syndrome which includes diarrhea, abdominal cramps, flushing, bronchoconstriction and cardiac valvular disease.
You need to consult a surgical oncologist for its immediate removal.
If you have no more clarifications then please rate the answer and close the thread.
Wishing your aunty a quick recovery.
Warm Regards
DR De
surgical oncologist
Detailed Answer:
Hi
Since your auntys neuroendocrine tumour has not spread to the liver in the PET scan and if the tumor is less than 2 cm with up to 6 polyps then it can be resected endoscopically, with subsequent interval follow-up.
If the tumors are measuring more than 2 cm with more than 6 polyps, then local surgical resection is recommended.
About 10 % of patients with neuroendocrine tumour are converted to carcinoid which can cause carcinoid syndrome which includes diarrhea, abdominal cramps, flushing, bronchoconstriction and cardiac valvular disease.
You need to consult a surgical oncologist for its immediate removal.
If you have no more clarifications then please rate the answer and close the thread.
Wishing your aunty a quick recovery.
Warm Regards
DR De
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Above answer was peer-reviewed by :
Dr. Prasad
Answered by
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