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What Does My HIV 1/2 Antigen/antibody 4th Generation Test Result Indicate?

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Posted on Fri, 9 Jan 2015
Question: My questions is I took these test after 24 days from exposure and within two weeks I was feeling real tired,dizzy,nausea, night sweats here and there

No fever,rash, swollen lymph nodes, no diarrhea, no vomiting.

My question is why is my absolute lymphocyte very low in the 695 area could it be due to hiv infection? But the test didn't pick it up?
Me and my new gf been having sex w a condom but last night she took it off cause she said your results said your good so we are okay.. she new about the encounter before we became bf and gf.. please respond thanks



HIV 1/2 ANTIGEN/ANTIBODY, FOURTH GENERATION W/RFL Lab: TXC
Test Name Results Reference Range HIV AG/AB, 4TH GEN NON-REACTIVE REFERENCE RANGE: NON-REACTIVE GLUCOSE 89 65-99 mg/dL
Fasting reference interval
UREA NITROGEN (BUN) 16 7-25 mg/dL CREATININE 1.11 0.60-1.35 mg/dL eGFR NON-AFR. XXXXXXX 90 > OR = 60 mL/min/1.73m2 eGFR XXXXXXX XXXXXXX 104 > OR = 60 mL/min/1.73m2 BUN/CREATININE RATIO NOT APPLICABLE 6-22 (calc) SODIUM 138 135-146 mmol/L POTASSIUM 4.3 3.5-5.3 mmol/L CHLORIDE 100 98-110 mmol/L CARBON DIOXIDE 27 19-30 mmol/L CALCIUM 9.8 8.6-10.3 mg/dL PROTEIN, TOTAL 7.9 6.1-8.1 g/dL ALBUMIN 5.0 3.6-5.1 g/dL GLOBULIN 2.9 1.9-3.7 g/dL (calc) ALBUMIN/GLOBULIN RATIO 1.7 1.0-2.5 (calc) BILIRUBIN, TOTAL 1.0 0.2-1.2 mg/dL ALKALINE PHOSPHATASE 39 L 40-115 U/L AST 17 10-40 U/L ALT 12 9-46 U/L CBC (INCLUDES DIFF/PLT) IG WHITE BLOOD CELL COUNT 4.4 3.8-10.8 Thousand/uL RED BLOOD CELL COUNT 4.90 4.20-5.80 Million/uL HEMOGLOBIN 14.3 13.2-17.1 g/dL HEMATOCRIT 43.7 38.5-50.0 % MCV 89.1 80.0-100.0 fL MCH 29.2 27.0-33.0 pg MCHC 32.8 32.0-36.0 g/dL RDW 15.7 H 11.0-15.0 % PLATELET COUNT 191 140-400 Thousand/uL ABSOLUTE NEUTROPHILS 3194 1500-7800 cells/uL ABSOLUTE LYMPHOCYTES 695 L 850-3900 cells/uL ABSOLUTE MONOCYTES 405 200-950 cells/uL ABSOLUTE EOSINOPHILS 62 15-500 cells/uL ABSOLUTE BASOPHILS 44 0-200 cells/uL NEUTROPHILS 72.6 % LYMPHOCYTES 15.8 % MONOCYTES 9.2 % EOSINOPHILS 1.4 % BASOPHILS 1.0 % HIV 1 RNA, QL TMA NOT DETECTED TXC REFERENCE RANGE: NOT DETECTED






doctor
Answered by Dr. Roopa Hiremath (10 hours later)
Brief Answer:
Absolute Lymphocytes at the lower range, but overall count normal

Detailed Answer:
Hi Mr. XXXXXXX

Welcome to Health care magic.

I understand your concern about HIV exposure and I can gauge the anxiety you have been through in the past few weeks.

Firstly, I want to explain few details about HIV infection to make you understand the situation better.

HIV is Human Immunodeficiency Virus which is most commonly spread through the sexual route. Other routes include through blood and from mother to child.

The semen and the vaginal secretions are rich with HIV particles in HIV infected individuals.

HIV enters the body through minor abrasions in the genital mucous membrane during intercourse and infects cells called macrophages which carry the virus to the local lymph nodes where it replicates and gets spilled into the blood. This takes about 4-11 days after exposure.

Hence, there is no test which can detect HIV within 4 days of exposure.

Antibodies against HIV are produced after 3 weeks to 3 months of exposure. Hence any test for HIV antibodies should be done after 3 weeks.

There is a window period where the individual may be HIV infected but may show negative results for HIV antibodies.

Hence it is best to do a confirmatory test for HIV antibodies after 3 months to be very sure.

Now coming to your situation, you are negative for HIV antibodies after 24 days after exposure.

I would suggest another test for antibodies after three months just to confirm your HIV negative status.

I would suggest usage of barriers(condoms) till confirmation of your HIV status.

Coming to your lymphocyte count, absolute lymphocyte count is at the lower range but when compared to the overall WBC count, it is normal.

Your other test results are in the normal range too.

Please get a confirmation test done after three months to ensure the negative HIV status.

If you have any more queries please get back to me.

Thanks.


Above answer was peer-reviewed by : Dr. Shanthi.E
doctor
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Follow up: Dr. Roopa Hiremath (1 hour later)
But I did both test hiv rna and the ag/ab at 24 days.. would it change later? Me and my gf been having sex w a condom but since I got my results she said your fine and took the condom off last night and I told her no to keep it on but she wanted it off im worried for her safety.. please get back doc.. she said she takes full responsibility for taking the condom off and that I am fine.. please get back other doctors say both those test are conclusive and I can have sex with my gf without a condom since we are in monogamous relationship..

Dont the HIV RNA test detect the virus? I took that test look on top at the 24 day mark plus the ag/ab 4 gen that is not conclusive?????? Im lost so I might be positive?????? Be honest with me..
doctor
Answered by Dr. Roopa Hiremath (18 minutes later)
Brief Answer:
HIV RNA is conclusive

Detailed Answer:
Hi Mr. XXXXXXX

Welcome back.

If you have undergone HIV RNA testing along with antibodies, then there is no necessity to do any confirmation test after 3 months.

I was under the impression that you have undergone only antibody testing after 24 days after exposure.

These tests are conclusive enough. There is no reason for worry.

Please let me know if I can assist you further.

Thanks.


Above answer was peer-reviewed by : Dr. Bhagyalaxmi Nalaparaju
doctor
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Follow up: Dr. Roopa Hiremath (11 minutes later)
Yes read my report up top it says both rna and ag/ab 4 gen.. please go over my labs again that I sent you.. thank you. I will be waiting for your response. Thanks
doctor
Answered by Dr. Roopa Hiremath (9 hours later)
Brief Answer:
No further testing required

Detailed Answer:
Hi Mr. XXXXXXX

I have seen your complete query. I had missed the RNA test as it had gone to the very end of the query.

HIV RNA test is conclusive enough.

No further testing required.

Thanks.


Above answer was peer-reviewed by : Dr. Vaishalee Punj
doctor
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Follow up: Dr. Roopa Hiremath (1 hour later)
What could of caused all those symptoms?
Like I notice I still get sore throats easily?
And I was really tired about 2 weeks after w nausea and very dizzy.. it lasted for a couple of days it felt like a concussion feeling.. I couldnt be out on the beach..im still scared that it might be hiv infection but the test missed it.. please respond.
doctor
Answered by Dr. Roopa Hiremath (15 hours later)
Brief Answer:
HIV test kits used are reliable kits

Detailed Answer:
Hi Mr. XXXXXXX

I understand your concern but the kits used for HIV testing undergo rigorous rounds of quality control before being used in labs.

Labs also have very strict protocol to follow when dealing with HIV testing.

Coming to the symptoms you have mentioned, they can occur in any viral infection. These symptoms do not suggest HIV infection.

Moreover, stress and anxiety can cause decreased immunity which can predispose for repeated infection.

Regarding feeling of dizziness, these symptoms have to be further evaluated.

I suggest you get in touch with a neurologist and get a through examination done to rule out other causes.

Please quit worrying about the test results and get a thorough evaluation done for your present symptoms.

Please let me know if I can assist you further.

Wishing you good health.

Thanks

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Above answer was peer-reviewed by : Dr. Chakravarthy Mazumdar
doctor
Answered by
Dr.
Dr. Roopa Hiremath

Infectious Diseases Specialist

Practicing since :2002

Answered : 877 Questions

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What Does My HIV 1/2 Antigen/antibody 4th Generation Test Result Indicate?

Brief Answer: Absolute Lymphocytes at the lower range, but overall count normal Detailed Answer: Hi Mr. XXXXXXX Welcome to Health care magic. I understand your concern about HIV exposure and I can gauge the anxiety you have been through in the past few weeks. Firstly, I want to explain few details about HIV infection to make you understand the situation better. HIV is Human Immunodeficiency Virus which is most commonly spread through the sexual route. Other routes include through blood and from mother to child. The semen and the vaginal secretions are rich with HIV particles in HIV infected individuals. HIV enters the body through minor abrasions in the genital mucous membrane during intercourse and infects cells called macrophages which carry the virus to the local lymph nodes where it replicates and gets spilled into the blood. This takes about 4-11 days after exposure. Hence, there is no test which can detect HIV within 4 days of exposure. Antibodies against HIV are produced after 3 weeks to 3 months of exposure. Hence any test for HIV antibodies should be done after 3 weeks. There is a window period where the individual may be HIV infected but may show negative results for HIV antibodies. Hence it is best to do a confirmatory test for HIV antibodies after 3 months to be very sure. Now coming to your situation, you are negative for HIV antibodies after 24 days after exposure. I would suggest another test for antibodies after three months just to confirm your HIV negative status. I would suggest usage of barriers(condoms) till confirmation of your HIV status. Coming to your lymphocyte count, absolute lymphocyte count is at the lower range but when compared to the overall WBC count, it is normal. Your other test results are in the normal range too. Please get a confirmation test done after three months to ensure the negative HIV status. If you have any more queries please get back to me. Thanks.