Get your Health question answered in 3 easy steps
A Doctor will be with you shortly
Ask a Doctor Now
177 Doctors are Online

What does FDG uptake in a blood vessel on pet scan indicate?

DOCTOR OF THE MONTH - Apr 2014
Apr 2014
User rating for this question
Very Good
Answered by

Radiologist
Practicing since : 2004
Answered : 6440 Questions
Question
What does FDG uptake in a blood vessel on pet scan indicate?
Posted Wed, 19 Mar 2014 in X-ray, Lab tests and Scans
 
 
Answered by Dr. Indu Kumar 1 hour later
Brief Answer: It indicates inflammatory changes in blood vessel Detailed Answer: Hello XXXX Thanks for writing to HCM FDG uptake in blood vessels indicates inflammatory changes. It may be due to atherosclerotic changes,vasculitis due to many causes like autoimmune diseases etc. FDG accumulates in the activated inflammatory cells due to overexpression of glucose transporters and activation of glycolytic enzymes. In atherosclerotic blood vessel changes,hybrid imaging method of PET/CT is useful for the localization of vulnerable plaques based on the uptake of FDG. In vasculitis there is infiltration of WBC within the vessel wall and it causes damage to the walls,this causes uptake of FDG. FDG uptake in blood vessels gives information about the extent of disease and its functional impairment. It is very helpful in early diagnosis of disease and its management. So, it is important to know proper clinical history of the patient. Hope i have answered your query. Further queries are most welcome. Take Care Dr.Indu XXXXXXX
Above answer was peer-reviewed by
 
Follow-up: What does FDG uptake in a blood vessel on pet scan indicate? 6 hours later
What if the WBC scan shows no inflammation or infection in the body? History of colon cancer with lynch syndrome.
 
 
Answered by Dr. Indu Kumar 17 hours later
Brief Answer: PET is more sensitive than WBC scan. Detailed Answer: Hello XXXX Thanks for writing back PET is more sensitive than WBC scan for detecting metastatic lesions.PET/CT is 3-D technique and it is highly sensitive. PET uptake in blood vessels occurs in many conditions like atherosclerosis,vasculitis,metastatic reactions etc. The most common site for metastatic spread of colon cancer is the liver.Other sites are the lungs, brain and bone.So,it is important to see for other sites of uptake and clinical correlation. Hope i have answered your query. Further queries are most welcome. Take Care Dr.Indu XXXXXXX
Above answer was peer-reviewed by
 
Share on Facebook
Share on Twitter
Share on Google+
Question is related to
Diseases and Conditions
Medical Topics

The user accepted the expert's answer

Ask a Radiologist

© Ebix, Inc. All Rights Reserved.
All the information, content and live chat provided on the site is intended to be for informational purposes only, and not a substitute for professional or medical advice. You should always speak with your doctor before you follow anything that you read on this website. Any health question asked on this site will be visible to the people who browse this site. Hence, the user assumes the responsibility not to divulge any personally identifiable information in the question. Use of this site is subject to our Terms & Conditions
Already Rated.
Your rating:

Ask a Doctor