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What Causes Positive Result For Treponema Pallidum Haemagglutination (TPHA)test?

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Posted on Wed, 17 Dec 2014
Question: Hi
Recently I was tested TPHA positive and vdrl negative at Medical centre,I consulted dermatology she suggested doxy antibiotics for two weeks
After two weeks I have to test again for my Muscat visa
Will it will be negative in 15 days or I have to take more medicine. I am 27 yrs old never ever had sex with any body till now
Hwz it possible of TPHA positive
I am really scared and don't know what to do next. Please help me out of this critical situation or else it will really affect my career and job
Regards
X
doctor
Answered by Dr. Bharatesh Devendra Basti (38 minutes later)
Brief Answer:
Confirmatory tests can be done.

Detailed Answer:
Hi
Thank you for query.I am Dr Bharatesh D Basti answering your query.
If there is no risk exposure there are chances of false positive also.You can go for FTA Abs test or EIA test for confirmation. Discuss with your doctor for investigation.Continue treatment .
The TPHA can take some days to come negative after treatment may be months.
Some selected jobs require syphilis negativity.
Go for confirmatory tests.
You can get back for any clarification.
Thank you
Dr Bharatesh D Basti
Dermatologist and venereologist.

Above answer was peer-reviewed by : Dr. Chakravarthy Mazumdar
doctor
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Follow up: Dr. Bharatesh Devendra Basti (18 hours later)
Any other medicines to be negative within 10 days
doctor
Answered by Dr. Bharatesh Devendra Basti (25 minutes later)
Brief Answer:
Discuss with your doctor regarding penicillin.

Detailed Answer:
Hi
Thank you for follow up query.
Usually penicillin is drug of choice.If allergic doxycycline is given.Either of them are similar for seroconversion.You can discuss with your doctor if you have any urgency for seroconversion.
You can get back for any clarification.
Thank you
Dr Bharatesh Basti
Above answer was peer-reviewed by : Dr. Prasad
doctor
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Follow up: Dr. Bharatesh Devendra Basti (1 hour later)
Respected Sir
As I had consulted at XXXXXXX but at present I am at my hometown, I want to clarify that if I will intake penicillin along with doxycycline, will it recover spe edily. Within 10 days, I need it urgently
After how many days I should go for tpha again to check the progress
Last test, I got positive 1:320
And what does it mean
doctor
Answered by Dr. Bharatesh Devendra Basti (1 hour later)
Brief Answer:
Go for confirmatory tests.

Detailed Answer:
Hi
Thank you for follow up query.
It is unlikely for tpha to come negative sooner as it is an antibody test. As said earlier It takes days- months for it to come negative after treatment. Antibodies exist even if there is no active infection.
So please go for confirmatory tests to confirm disease after discussion with your doctor.

Progression of disease is not monitored by tpha test as it tends to remain positive for long time.

Visa refusal depends on type of job. They may not consider it as ground for refusal in many jobs.

You can get back for any clarification.

Thank you
Dr Bharatesh D Basti
Note: Consult a Sexual Diseases Specialist online for further follow up- Click here.

Above answer was peer-reviewed by : Dr. Shanthi.E
doctor
Answered by
Dr.
Dr. Bharatesh Devendra Basti

Dermatologist

Practicing since :1998

Answered : 1764 Questions

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What Causes Positive Result For Treponema Pallidum Haemagglutination (TPHA)test?

Brief Answer: Confirmatory tests can be done. Detailed Answer: Hi Thank you for query.I am Dr Bharatesh D Basti answering your query. If there is no risk exposure there are chances of false positive also.You can go for FTA Abs test or EIA test for confirmation. Discuss with your doctor for investigation.Continue treatment . The TPHA can take some days to come negative after treatment may be months. Some selected jobs require syphilis negativity. Go for confirmatory tests. You can get back for any clarification. Thank you Dr Bharatesh D Basti Dermatologist and venereologist.