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What Causes Persistent Loose Stool And Weight Loss After Kidney Transplant Surgery?

Posted on Wed, 29 Jun 2016

Question: Hello sir
I hv gone through kidney transplant 2 months back.
I Was taking cellcept 1gm twice a day.
After 1 & half month of operation, my stomach got upset n I m suffering frm loose motions till date.
4-5 loose motions cm daily.
My dr reduced d dose of cellcept to 500mg twice a day.
Nw there is a improvement 1 day n 2nd day it is d same
My weight too is reducing day by day
Nw my dr is advising me to stop cellcept for 1 week.
I am taking sporlac XXXXXXX 3 times a day 2 sachets at a time.
What do u recommend?

Answered by Dr. Dr. P. T. Patil (53 minutes later)

Brief Answer:
These are known side effects of Mycophenolate Mofetil (Cellcept)

Detailed Answer:
Hello
Thanks for your query ,based on the facts that you have posted it appears that you have undergone Renal Transplant very recently and have been prescribed Immuno Suppresant medication Mycophenote mofetil and now getting loose motions
.
Diarrhea and vomiting are the It is the known side effect of this medication .

There is no harm in stopping this drug for a while and start with 500mg along with steroids and gradually increase it to 1 gm daily. .

Taking H2 receptor antagonist (Pantaprazole ) and Loperamide will help to reduce frequency of loose motions .

Take soft diet with curd and rice .

It is very common side of this drug but one gradually gets accustomed .

Hope I have answered your query ,please feel free to ask if you have more questions , I shall be happy to help you .
Thanks and Regards.
Dr.Patil.

Above answer was peer-reviewed by : Dr. Chakravarthy Mazumdar

Follow up: Dr. Dr. P. T. Patil (17 minutes later)

I hv loose motions for about 15 days. Pls suggest exact dose of medication .
is thr any side effect to my kidney. Sir Is this related to septron DS half tablet that I am taking. I hv noticed that my loose motions starts aftr taking d same

Answered by Dr. Dr. P. T. Patil (3 minutes later)

Brief Answer:
You have to take medications under supervision of your Physician

Detailed Answer:
Hello
Thanks for follow up .

You have to take these medications twice daily and adjust the dose depending upon the response and under supervision of your physician .

Septran does not cause loose motions .Loose motions are basically due to side effect of Mycophenolate Mofetil .

Thanks and Regards.
Dr.Patil.

Above answer was peer-reviewed by : Dr. Chakravarthy Mazumdar

Follow up: Dr. Dr. P. T. Patil (41 minutes later)

Pls ans my questions in detail
1. I don't want to stop cellcept
is thr any side effect of stopping it during or aftr I stop taking it
2 my weight is reducing day by day
when will it be normal
3 which fruit or vegetables can I eat in diet?
4. is this problem means kidney rejection?

Answered by Dr. Dr. P. T. Patil (20 minutes later)

Brief Answer:
There is no harm in stopping Cellcept for a week .

Detailed Answer:
Hello
Thanks for follow up .

1)There is no harm in stopping Cellcept for a week till your loose motions are under control .

2) Renal transplant is a supra major surgery and take 3- 4 months for full recovery and to gain your normal eight .It should be normal once your digestive system becomes normal .

3)You ca take Apples ,Pomegranate ,Banana etc

4) It is not Kidney rejection .Kidney rejection usually presents with deranged renal function like raised creatinine ,reduced urine output,edema over body due to fluid retention etc.

Hope I have answered your query ,please feel free to ask if you have more questions , I shall be happy to help you .
Thanks and Regards.
Dr.Patil.

Note: For further queries related to kidney problems and comprehensive renal care, talk to a Nephrologist. Click here to Book a Consultation.

Above answer was peer-reviewed by : Dr. Chakravarthy Mazumdar