Brief Answer:
Mastocytosis is neoplastic proliferation of mast cells

Detailed Answer:
Hello,
Thanks for posting your query on HealthcareMagic.
Mastocytosis is a condition wherein the mast cells are increased in body.
Increased number of mast cells either infiltrate the blood or the tissues like skin etc.
Mast cells are normally present in tissues and are responsible for immune reaction against allergens.
The mast cell counterpart in blood is a basophil.
Mastocytosis is one of the chronic myeloproliferative disorder.
However, mastocytosis can only be diagnosed when other infectious conditions are ruled out.
Treatment of mastocytosis is aimed to reduce the number of mastocytes and to minimize the ill-effects caused by degranulation of the mast cells.
Thus, consulting a hematologist is required for further work up and thus management.

Thanks and take care
Dr Shailja Puri

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Brief Answer:
Elevated MCV suggests large sized red blood cells

Detailed Answer:
Hello and welcome again,
Elevated MCV suggests that there is presence of large sized red blood cells.
The MCV value has to correlated along with MCH, MCHC, red blood cell counts, and hemoglobin levels for more information.
Thus, post these investigations for more information.

Thanks and take care
Dr Shailja Puri

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