Sign-in to Ask A Doctor - 24x7
OR
Sign in with Google
What Causes Elevated Thrombin Level?
Brief Answer:
Additional tests.
Detailed Answer:
Hi XXXX
Thrombin time is a measure of how long the blood's plasma, or the liquid portion of the blood, takes to form a clot. This test provides information about how well one particular blood component, called fibrinogen, is working.
A normal thrombin time is 11.3 to 18.5 seconds.
A longer thrombin time can indicate low fibrinogen, high fibrinogen, or fibrinogen that's not working properly. It can also be because of medications that affect blood clotting, such as heparin, argatroban, hirudin, or hirulog.
A longer thrombin time can be caused by proteins in the blood from the medical conditions multiple myeloma or amyloidosis, or from antibodies that developed from earlier exposure to bovine thrombin.
Conditions such as disseminated intravascular coagulation (DIC) or abnormal fibrinolysis impair fibrin formation and can also lead to a prolonged thrombin time, as can conditions such as end stage liver disease or malnutrition.
If thrombin time is abnormal, additional tests may be needed, including fibrinogen activity assay ,fibrinogen antigen assay, and liver function tests.
Consult your doctor regarding these tests.
Regards
DR De
Additional tests.
Detailed Answer:
Hi XXXX
Thrombin time is a measure of how long the blood's plasma, or the liquid portion of the blood, takes to form a clot. This test provides information about how well one particular blood component, called fibrinogen, is working.
A normal thrombin time is 11.3 to 18.5 seconds.
A longer thrombin time can indicate low fibrinogen, high fibrinogen, or fibrinogen that's not working properly. It can also be because of medications that affect blood clotting, such as heparin, argatroban, hirudin, or hirulog.
A longer thrombin time can be caused by proteins in the blood from the medical conditions multiple myeloma or amyloidosis, or from antibodies that developed from earlier exposure to bovine thrombin.
Conditions such as disseminated intravascular coagulation (DIC) or abnormal fibrinolysis impair fibrin formation and can also lead to a prolonged thrombin time, as can conditions such as end stage liver disease or malnutrition.
If thrombin time is abnormal, additional tests may be needed, including fibrinogen activity assay ,fibrinogen antigen assay, and liver function tests.
Consult your doctor regarding these tests.
Regards
DR De
Above answer was peer-reviewed by :
Dr. Vinay Bhardwaj
My liver functions were normal.....and I don't believe I have DIC as nothing has shown. Is it possible that I have something that is not life threatening?
Brief Answer:
Minorly high
Detailed Answer:
Hi XXXX
A normal thrombin time varies from 11.3 to 20 seconds.
Your thrombin time is only 22.8 which is very slightly high and since your Liver Function Test is normal i think you do not need to worry.
If you do not have any clarifications, you can close the discussion and rate the answer. Wish you good health.
Regards
DR De
Minorly high
Detailed Answer:
Hi XXXX
A normal thrombin time varies from 11.3 to 20 seconds.
Your thrombin time is only 22.8 which is very slightly high and since your Liver Function Test is normal i think you do not need to worry.
If you do not have any clarifications, you can close the discussion and rate the answer. Wish you good health.
Regards
DR De
Note: Do you have more questions on diagnosis or treatment of blood disorders? Ask An Expert/ Specialist Now
Above answer was peer-reviewed by :
Dr. Vaishalee Punj
Answered by
Get personalised answers from verified doctor in minutes across 80+ specialties
