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What Causes Elevated Liver Enzymes?

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Posted on Wed, 26 Nov 2014
Question: Sir Very good morning
SGOT 40, SGPT 110 and ALKALINE PHOSPHATASE is 159. As per the report they all are high pls help me how serious is the situation and also guide me what necessary step should i take to live normally.

regards

XXXXXX
doctor
Answered by Dr. Indu Kumar (14 minutes later)
Brief Answer:
Increased SGPT level indicates liver injury.

Detailed Answer:
Hello XXXXXX

Your findings suggests raised SGPT,Alkaline phosphatase and SGOT level.
Increased SGPT level indicates liver injury.Increase in SGPT may be due to many reasons like hepatitis,alcohol intake,altered lipid profile,medicines,auto immune causes etc.
SGOT is non specific and it increases in many conditions.

Alkaline phosphatase increases in bone,liver disorders etc.It need clinical correlation.
Urine test is within normal limit.

In your case,increased SGPT may be related to alcohol intake.It is good that you have quit drinking and increased your physical activity.

You need few more investigations like routine hemogram,random blood sugar,lipid profile.
Ultrasound of abdomen should be done to assess liver.

I suggest my patients to take tablet ursodeoxycholic acid 300 mg twice daily for three months.It will help in regeneration of liver cells.

You should avoid red meat and high fat milk products.
You will be fine soon.

Get well soon.
Hope I have answered your question.
Further queries are most welcome.

Take Care
Dr.Indu XXXXXXX
Above answer was peer-reviewed by : Dr. Chakravarthy Mazumdar
doctor
Answered by
Dr.
Dr. Indu Kumar

Radiologist

Practicing since :2004

Answered : 6729 Questions

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What Causes Elevated Liver Enzymes?

Brief Answer: Increased SGPT level indicates liver injury. Detailed Answer: Hello XXXXXX Your findings suggests raised SGPT,Alkaline phosphatase and SGOT level. Increased SGPT level indicates liver injury.Increase in SGPT may be due to many reasons like hepatitis,alcohol intake,altered lipid profile,medicines,auto immune causes etc. SGOT is non specific and it increases in many conditions. Alkaline phosphatase increases in bone,liver disorders etc.It need clinical correlation. Urine test is within normal limit. In your case,increased SGPT may be related to alcohol intake.It is good that you have quit drinking and increased your physical activity. You need few more investigations like routine hemogram,random blood sugar,lipid profile. Ultrasound of abdomen should be done to assess liver. I suggest my patients to take tablet ursodeoxycholic acid 300 mg twice daily for three months.It will help in regeneration of liver cells. You should avoid red meat and high fat milk products. You will be fine soon. Get well soon. Hope I have answered your question. Further queries are most welcome. Take Care Dr.Indu XXXXXXX