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What Causes Elevated APTT

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Posted on Wed, 26 Feb 2014
Question: Helo doctor, In the past twice i got faint positive around day 40 and then started my period within 45 days.so doctor took blood test for me and the results are below: Free T4 : 1.59ng/dl TSH 3 RD GEN : 1.52 nd/dl ANTI - CARDIOLIPIN IgM: 5.30u/ml ANTI - CARDIOLIPIN IgG : 4.10u/ml aPTT observed value : 46.0 sec test value : 28.0 sec My doctor said that all are normal except for apTT which is slightly elevated.i do not understand what it means.She said that she will start the treatment from next cycle and to try naturally this month. This month period got delayed and i took a pregnancy test at home at 40th day and got a positive imeediately. Met with the doctor and she has given me strone 200 mg day and night and ENOXAPARIN 4ml injection for one week and then scan.Should i use this injection till delivery or it is only for stabilizing my pregnancy.i am really worried.Today is 44th day and everything is going fine.please clarify me about aPTT and how it may affect my pregnancy.
doctor
Answered by Dr. Mahesh Koregol (2 hours later)
Brief Answer: Continue Detailed Answer: Hi, The tests you mentioned are to diagnose antiphospholipid antibodies. Since aPTT is elevated your doctor has started you on injections which should be taken daily till 32 weeks of pregnancy. Please get serum beta hCG blood test to confirm pregnancy and this value will be helpful to corelate if you abort again. Get an ultrasound scan ( TVS ) to confirm pregnancy by locating gestational sac and heart beat before starting the injection as it is advisable to start injections only after confirming heart beat. Let me know if you have anymore queries. Regards, Dr. Mahesh Koregol
Above answer was peer-reviewed by : Dr. Chakravarthy Mazumdar
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Follow up: Dr. Mahesh Koregol (2 hours later)
Doctor, Thank you for your response.i forgot to mention LUPUS ANTICOAGULANT which is normal too .Is it possible to supplement by taking anti coagulant pills and not injections.Is there no way other than to take injections daily.What does elevated aPTT value mean?.is it a serious problem?
doctor
Answered by Dr. Mahesh Koregol (1 hour later)
Brief Answer: No Detailed Answer: Hi No. Its not a serious problem. You can opt for aspirin tablets instead. There is nothing serious about it. You can even opt for not taking injections. No problem. Dont worry. First confirm fetal heart beat and then decide in medicine regards
Above answer was peer-reviewed by : Dr. Chakravarthy Mazumdar
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Answered by
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Dr. Mahesh Koregol

Infertility Specialist

Practicing since :2000

Answered : 3829 Questions

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What Causes Elevated APTT

Brief Answer: Continue Detailed Answer: Hi, The tests you mentioned are to diagnose antiphospholipid antibodies. Since aPTT is elevated your doctor has started you on injections which should be taken daily till 32 weeks of pregnancy. Please get serum beta hCG blood test to confirm pregnancy and this value will be helpful to corelate if you abort again. Get an ultrasound scan ( TVS ) to confirm pregnancy by locating gestational sac and heart beat before starting the injection as it is advisable to start injections only after confirming heart beat. Let me know if you have anymore queries. Regards, Dr. Mahesh Koregol