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What Causes Elevated GGT And Bilirubin Levels In Adults?

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Posted on Tue, 5 May 2015
Question: Hi Doctor,

My name is XXXX and I am 35 year old XXXXXXX male. I am a non-smoker, non-alcoholic and moderate non-vegetarian (once in 10 days). I weigh 69 kgs and have a moderately active life. My Lipid Profile (cholesterol, Triglycerides etc) are out of normal range. This has been the case since 2012 when I started tracking these parameters. Off late my SGPT and SGOT levels. I have no symptoms of loss of appetite, tiredness, weight loss etc (I have gained 2-3 kgs in last two months without corresponding increase in my food intake). My urine and stool are of normal color and regular frequency. My BP is normal. I have attached last 3 reports since Jul 2014.

What could be the reasons for my Lipid Profile and LFT results to be out of range? What should I do?

Seek your recommendations.

Regards
XXXX
doctor
Answered by Dr. Divakara (35 hours later)
Brief Answer:
It could be due to Genetic disease.

Detailed Answer:
HI XXXX

Greetings from Dr.Divakara.P
Thanks for posting your query.

I went through your reports . There is mild elevation in your Total Bilirubib and GGT ( liver enzyme ) . This can happen in an viral infection and there is nothing to be worried about it . One more possibility is some genetic disease like Rotar syndrome or XXXXXXX syndrome where there will be mild elevation in Bilirubin . Even these syndromes are harmless and nothing needs to be done for them . So just relax.

Coming to your cholesterol levels they are very much deranges especially Triglycerides . For your age these values are extremely high. There is a high possibility that the elevated cholesterol levels runs in your family . ( due to genes )

You need to be started on medication like Tablet Atorvastatin+Fenofibrate. I know you are taking Lipotab but how effective it is is doubtful .

Along with that you need to do a proper diet and good aerobic exercise.

Diet : Avoid Sweets , Carbonated drinks ( pepsi, Coco cola ), Avoid Non Veg especially Mutton , Beef , Egg yolk strictly , occasionally you can take Chicken and fish.
Eat more of vegetables , fruits and drink plenty of water.

Exercise : Do aerobic exercise like Brisk walking , Jogging , Running , Cycling , Swimming for atleast 20 minutes per day . Be regular do it daily .
Also increase the intensity or duration of exercise every 2 weeks .


Keep doing these and repeat Lipid Profile after 3 months and revert back .

Hope this information was useful to you.
Any clarifications feel free to ask .

Regards.


Above answer was peer-reviewed by : Dr. Chakravarthy Mazumdar
doctor
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Follow up: Dr. Divakara (6 hours later)
Dear Dr Divakara,

Thank you for your reply.

I was taking Isabgol along with Lipotab and during that period the Lipid profile improved. But then I started feeling bloated and discomfort with Isabgol so I stopped. My doctor hadrecommended Fibotab (by Torrent Pharma) as a replacement for Isabgol but that is unavailable at Pharmacies. Can you recommend a suitable replacement for Fibotab?

What about my high levels of SGOT and SGPT? Do you recommend getting myself investigated for determined the cause of high levels of Bilirubin , SGOT and SGPT? Though I have no problems, what could be long term implication of these high levels?

Awaiting your response.

Thanks and regards
XXXX








doctor
Answered by Dr. Divakara (38 minutes later)
Brief Answer:
Fibotab won't help for cholesterol

Detailed Answer:
HI

Ispagol or Fibotab are bulk forming agents mainly used in people with diarrhoea/Constipation . They will not help in reducing your cholesterol levels.

Anyhow if you still insists for that you can ask for Polycarbophil calcium ( this is the content of Fibotab ) brand name is Shreeji.

As of your SGOT , SGPT levels are concerned your recent report showed it as normal . Only Bilirubin and GGT were elevated and since it is very mild elevation I don't recommend any evaluation for that.

There are no long term implications that you need to worry.

Hope this information was useful to you.
Any clarification feel free to ask .

Regards.
Above answer was peer-reviewed by : Dr. Chakravarthy Mazumdar
doctor
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Follow up: Dr. Divakara (6 minutes later)
Thanks for your quick response.

My report dated 12 Apr 2015 shows SGOT at 65 (range 15-37) and SGPT at 122 (range 16-63) and both are marked as high. Bilirubin at 1.61 and GGT at 161.

I hope you are referring to correct report of mine.

Regards
XXXX
doctor
Answered by Dr. Divakara (48 minutes later)
Brief Answer:
Nothing needs to be done now.

Detailed Answer:
HI

I went through that but again these are minor elevations and nothing needs to be done . Such kind of elevations can happen due to minor viral infections or even due to intake of certain medications .

Do one thing repeat it after 3 months again and if the values are more than the present one then you can undergo the following tests.

IgM and IgG Hepatitis A antibodies, HBSAg, HCV RNA, IgM Anti-HBE Antibodies , Serum TSH and Ultrasound Abdomen .

But I feel that there is no need for any further evaluation as of now .

Regards.
Above answer was peer-reviewed by : Dr. Chakravarthy Mazumdar
doctor
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Follow up: Dr. Divakara (26 minutes later)
Thanks a lot Dr.

Interacting with you has been very helpful. Will follow the regime advised by you and redo the test after 3 months. Hopefully everything will be underr control by then.

Thanks once again

Regards
XXXX
doctor
Answered by Dr. Divakara (24 minutes later)
Brief Answer:
Take care.

Detailed Answer:
HI

Take care and do start the cholesterol medicine . Also get your siblings ( brothers and sisters ) to get their Cholesterol checked as there is a high possibility of them too having high values .

Regards.
Note: For further queries related to coronary artery disease and prevention, click here.

Above answer was peer-reviewed by : Dr. Chakravarthy Mazumdar
doctor
Answered by
Dr.
Dr. Divakara

Internal Medicine Specialist

Practicing since :2006

Answered : 2358 Questions

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What Causes Elevated GGT And Bilirubin Levels In Adults?

Brief Answer: It could be due to Genetic disease. Detailed Answer: HI XXXX Greetings from Dr.Divakara.P Thanks for posting your query. I went through your reports . There is mild elevation in your Total Bilirubib and GGT ( liver enzyme ) . This can happen in an viral infection and there is nothing to be worried about it . One more possibility is some genetic disease like Rotar syndrome or XXXXXXX syndrome where there will be mild elevation in Bilirubin . Even these syndromes are harmless and nothing needs to be done for them . So just relax. Coming to your cholesterol levels they are very much deranges especially Triglycerides . For your age these values are extremely high. There is a high possibility that the elevated cholesterol levels runs in your family . ( due to genes ) You need to be started on medication like Tablet Atorvastatin+Fenofibrate. I know you are taking Lipotab but how effective it is is doubtful . Along with that you need to do a proper diet and good aerobic exercise. Diet : Avoid Sweets , Carbonated drinks ( pepsi, Coco cola ), Avoid Non Veg especially Mutton , Beef , Egg yolk strictly , occasionally you can take Chicken and fish. Eat more of vegetables , fruits and drink plenty of water. Exercise : Do aerobic exercise like Brisk walking , Jogging , Running , Cycling , Swimming for atleast 20 minutes per day . Be regular do it daily . Also increase the intensity or duration of exercise every 2 weeks . Keep doing these and repeat Lipid Profile after 3 months and revert back . Hope this information was useful to you. Any clarifications feel free to ask . Regards.