Brief Answer: Following are sign and symptoms Detailed Answer: Hello, Thanks for your query. Following are signs and symptoms of depression: -Depressed mood to a degree that is definitely abnormal for the individual, present for most of the day and almost every day, largely uninfluenced by circumstances, and sustained for at least 2 weeks. -Marked loss of interest or pleasure in activities that are normally pleasurable; -Lack of emotional reactions to events or activities that normally produce an emotional response -Objective evidence of marked psychomotor retardation or agitation (remarked on or reported by other people) -Marked loss of libido. -A reduction in energy or activity; -Loss of self confidence or feelings of inadequacy -unreasonable feelings of self-reproach or excessive and inappropriate guilt -Recurrent thoughts of death or suicide, or any suicidal behaviour -Sleep disturbance of any type; -Change in appetite (decrease or increase) with corresponding weight change. To diagnose depression there is no need of presence of every sign and symptom in one patient. Treatment is needed when these symptoms affect personal, social and occupational life of the person. I hope this information has been both informative and helpful for you. In case of any doubt, I will be available for follow ups. Wish you good health. Regards

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