Get your Health question answered in 3 easy steps
A Doctor will be with you shortly
Ask a Doctor Now
130 Doctors are Online

What are the side effects of methotrexate on bladder and vagina?

Mar 2016
User rating for this question
Very Good
Answered by

Practicing since : 2011
Answered : 4045 Questions
What are the side effects of methotrexate related to the badder and the vagina?
Posted Mon, 2 Sep 2013 in Women's Health
Answered by Dr. S Patra 1 hour later
Brief Answer:
Methotrexate has several side effects.

Detailed Answer:

Thanks for writing to us.

Side effects occur due to high dose of Methotrexate. The following ones are related to bladder and vagina:

1) Bladder inflammation and cancer (in long term use).
2) Renal impairment and hematuria (bloody urine).
3) Vaginal pruritus (itching) and infection.
4) Vaginal bleeding or spotting.

Folinic acid supplement is given as antidote of Methotrexate toxicity. If the patient suffer from any of these symptoms, it is worthwhile to consult the treating doctor and ask for folinic acid supplement.

Hope, above information is quite helpful. Let me know, if you need any clarification.

Wish your good health. Good luck.

Dr Soumen
Above answer was peer-reviewed by
Share on Facebook
Share on Twitter
Share on Google+
Question is related to
Diseases and Conditions
Medical Topics

The user accepted the expert's answer

Ask an OBGYN

© Ebix, Inc. All Rights Reserved.
All the information, content and live chat provided on the site is intended to be for informational purposes only, and not a substitute for professional or medical advice. You should always speak with your doctor before you follow anything that you read on this website. Any health question asked on this site will be visible to the people who browse this site. Hence, the user assumes the responsibility not to divulge any personally identifiable information in the question. Use of this site is subject to our Terms & Conditions
Already Rated.
Your rating:

Ask a Doctor